Monoacylglycerol lipase (MAGL) is a serine hydrolase that play a major role in the degradation of 2-arachidonoylglycerol, an endocannabinoid neurotransmitter implicated in several physiological processes. Recent studies have shown the possible role of MAGL inhibitors as anti-inflammatory, anti-nociceptive and anti-cancer agents.
Part of our team is dedicated to empowering and collaborating with professors and researchers at universities worldwide that want to be involved in the identification of new MAGL inhibitors.
We welcome all the possible collaborations. We can provide a) in silico screening, b) experimental screening on the MAGL target, c) cellular assays and d) we can also supply reversible MAGL inhibitors for in vivo experiments.
For requesting more information, please send an email to Prof. Tiziano Tuccinardi